Dexketoprofen trometamol-loaded poly-lactic-co-glycolic acid (PLGA) nanoparticles: Preparation, <i>in vitro</i> characterization and cyctotoxity
نویسندگان
چکیده
منابع مشابه
Synthesis and Characterization of Ursolic Acid Loaded Poly (Lactic-Co-Glycolic Acid) Nanoparticles and Caffiene Loaded Poly (Lactic-Co-Glycolic Acid) Nanoparticles in Colorectal Cancer Cell Line
Colorectal cancer is the fourth most frequently diagnosed cancer and the second leading cause of cancer death. About 96,830 new cases of colon cancer and approximately 40,000 cases of rectal cancer will occur and 50,310 people will die of colon and rectal cancer combined[1]. The long term survival rate of colon cancer patients treated by conventional modalities such as surgery, radiation, and c...
متن کاملCurcumin-loaded poly lactic-co-glycolic acid nanoparticles effects on mono-iodoacetate -induced osteoarthritis in rats
Curcumin has been found to be very efficacious against many different types of diseases. However, the major disadvantage associated with the use of curcumin is its low systemic bioavailability. In the present study the protective effects of curcumin-loaded poly lactic-co-glycolic acid nanoparticles (nanocurcumin) against mono-iodoacetate-induced osteoarthritis in rats was inves...
متن کاملAmphotericin B in poly(lactic-co-glycolic acid) (PLGA) and dimercaptosuccinic acid (DMSA) nanoparticles against paracoccidioidomycosis.
OBJECTIVES The present study reports on the preparation and testing of a desoxycholate amphotericin B (D-AMB) sustained delivery system based on poly(lactic-co-glycolic acid) (PLGA) and dimercaptosuccinic acid (DMSA) polymeric blends (Nano-D-AMB) aimed at reducing the number of AMB administrations required to treat mycosis. METHODS BALB/c mice were infected with the yeast Paracoccidioides bra...
متن کاملPoly (Lactic-Co-Glycolic) Acid (PLGA) Adjuvant for Immunotherapy
Nowadays, there are several efforts in immunotherapy especially biodegradable and biocompatible nano-polymers are using as immunomodulatory to induce cell mediated immune responses [1]. The advantages of nanoparticles have been proved to be potent immunomodulators in several kinds of vaccines to control a release of antigen, higher quality and quantity of immune responses and protect the integr...
متن کاملPreparation, characterization, and in vivo study of rhein-loaded poly(lactic-co-glycolic acid) nanoparticles for oral delivery
A novel rhein formulation based on poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) suitable for oral administration was developed in this study. The designed nanosystems were obtained by a modified spontaneous emulsification solvent diffusion method. The morphology of rhein-loaded PLGA NPs showed a spherical shape with a smooth surface, without any particle aggregation. Mean size of th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2019
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v18i1.1